The notch depth index (NDI) and the predictability of placental disorders

Studies have shown the utility of uterine artery (UtA) doppler in prediction placental disorders pregnancy, mainly hypertensive pregnancy (HDP) and fetal growth restriction. The most studied parameters are pulsatility index (PI), resistance (RI), or presence a diastolic notch (DN). While PI RI quantitative measures, attempts to quantify DN for HDP limited. We aimed an attempt improve disorders. A retrospective study patients who had scan at 16-26 weeks gestation delivered two tertiary academic centers. UtA was measured all patients. When present, it quantified using Notch Depth Index (NDI) (Figure 1). Patients developed induction labor due suspected restriction (estimated weight < 10th percentile) were compared with those did not. Out 262 women, 40 (15.3%) (17 HDP, 13 FGR, 10 both). Of these patients, 6 (15%) unilateral DN, 7 (17.5%) bilateral 9 (22.5%) mean >95th percentile. ROC curve NDI is presented Figure 2. AUC 0.703 (95% CI 0.525-0.882), 0.668 0.491-0.844) PI. cut-off 0.158 yielded sensitivity 84.6% specificity 71.4% Using this cut-off, 19 out (47.5%) would been predicted be high risk during second trimester can predictability disorders, help better plan follow up risk.View Large Image ViewerDownload Hi-res image Download (PPT)